Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2499)
Related Products (2499)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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PfPKG-IN-1
0 ImagesCat. No.: HY-145233CAS No.: 2866493-89-0PfPKG-IN-1 is a imidazole-based inhibitor of Plasmodium falciparum cGMP-dependent protein kinase (PfPKG).
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Cinchonine hydrochloride
0 ImagesCat. No.: HY-W011241CAS No.: 5949-11-1Synonyms: (8R,9S)-Cinchonine hydrochloride; LA40221 hydrochloride
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Antimalarial agent 13
0 ImagesCat. No.: HY-147198CAS No.: 431884-01-4Antimalarial agent 13 (Compound 1) is a potent antimalarial agent. Antimalarial agent 13 shows inhibition with EC50 values of 124 nM and 2.5 μM against P. falciparum parasite and HepG2, respectively.
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Pefloxacin-d5
0 ImagesSynonyms: Pefloxacinium-d5Pefloxacin-d5 (Pefloxacinium-d5) is the deuterium labeled Pefloxacin (HY-B0147). Pefloxacin (Pefloxacinium) is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 μg/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti-Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies.
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JMI-346
0 ImagesCat. No.: HY-147850CAS No.: 2091841-46-0JMI-346 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-346 inhibits the growth of CQS (3D7; IC50=13 µM) and CQR (RKL-9; IC50=33 µM) strains of P. falciparum. JMI-346 has the potential to be used as an anti-malarial agent.
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Drupacine
0 ImagesCat. No.: HY-N3786CAS No.: 49686-57-9Drupacine is a natural product, that can be isolated from Cephalotaxus harringtonia. Drupacine shows nematotoxicity and anticancer activity.
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Bacopasaponin C (Standard)
0 ImagesCat. No.: HY-N6015RCAS No.: 178064-13-6Bacopasaponin C (Standard) is the analytical standard of Bacopasaponin C (HY-N6015). This product is intended for research and analytical applications. Bacopasaponin C is an orally active natural glycoside. Bacopasaponin C can be isolated from Bacopa monniera. Bacopasaponin C inhibits Verapamil (HY-14275)-stimulated P-gp ATPase activity with an IC50 of 57.83 μg/mL. Bacopasaponin C has antitumor activity against sarcomas. Bacopasaponin C has antiparasitic activity against Leishmania donovani.
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ent-Rhizocarpic acid
0 ImagesCat. No.: HY-177540CAS No.: 3061155-24-3ent-Rhizocarpic acid is an enantiomer of Rhizocarpic acid. ent-Rhizocarpic acid has more potent antibacterial and antiparasitic activity against Staphylococcus aureus (ATCC 25923) and Giardiaduodenalis 713 compared to Rhizocarpic acid. ent-Rhizocarpic acid also has a weak but selective antitumor activity against NS-1 cells.
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Ipflufenoquin (Standard)
0 ImagesCat. No.: HY-134338RCAS No.: 1314008-27-9(R)-Omeprazole (sodium) (Standard) is the analytical standard of (R)-Omeprazole (sodium). This product is intended for research and analytical applications. (R)-Omeprazole sodium is a gastric acid resistant compound with activity to inhibit gastric acid secretion. (R)-Omeprazole sodium is metabolized in vivo, and its metabolism is primarily affected by cytochrome P450 enzymes. The interaction between (R)-Omeprazole sodium and mannitol may affect its bioavailability in formulations. (R)-Omeprazole sodium exhibits reversible direct and metabolism-dependent inhibition of CYP2C19.
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Antiparasitic agent-16
0 ImagesCat. No.: HY-149080CAS No.: 3046451-89-9Antiparasitic agent-16, a pyridine-thiazolidinone, has anti-Trypanosoma cruzi and leishmanicidal activities. Antiparasitic agent-16 has IC50s of 1.0 μM and 0.6 μM against trypomastigote and amastigote forms of T. cruzi. Antiparasitic agent-16 has IC50s of 150.2 μM and 16.75 μM against trypomastigote and amastigote forms of L. amazonensis. Antiparasitic agent-16 induces parasite cell death through necrosis induction. Antiparasitic agent-16 induces morphological changes such as shortening, retraction and curvature of the parasite body and leakage of internal content with T. cruzi trypomastigotes.
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6-O-Methylcatalpol
0 Images6-O-Methylcatalpol can be isolated from the roots of Scrophularia ningpoensis. 6-O-Methylcatalpol has anti-protozoal activity against Trypanosoma b. rhodesiense and Leishmania donovani (IC50: 32.5 and 8.3 μg/mL).
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Antitrypanosomal agent 7
0 ImagesCat. No.: HY-147550CAS No.: 2492436-38-9Antitrypanosomal agent 7 (compound 18c) is a potent and antitrypanosomal agent with favorable ADME properties. Antitrypanosomal agent 7 is > 2-fold more potent against Trypanosoma brucei (T. brucei) than Nifurtimox, with an IC50 value of 0.71 μM. Antitrypanosomal agent 7 has strong interaction to DNA and can bind with high selectivity to AT-rich DNA.
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Anti-infective agent 6
0 ImagesCat. No.: HY-151612CAS No.: 2839192-35-5Anti-infective agent 6 (compound 28) is a potent anti-infectious agent. Anti-infective agent 6 shows a good activity against P. falciparum F32-ART (IC50=1.4 μM) with a good selectivity index (SI>36). Anti-infective agent 6 also shows a potency against L. donovani (IC50=3.5 μM).
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Oxibendazole (Standard)
0 ImagesOxibendazole (Standard) is the analytical standard of Oxibendazole. This product is intended for research and analytical applications. Oxibendazole is an effective benzimidazole anthelmintic and is against nema-tode infections. Oxibendazole can induces apoptosis and has anti-cancer and anti-inflammation activities.
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Metronidazole Benzoate (Standard)
0 ImagesSynonyms: Benzoyl metronidazole (Standard)Metronidazole Benzoate (Standard) is the analytical standard of Metronidazole Benzoate. This product is intended for research and analytical applications. Metronidazole Benzoate, derives from a metronidazole and a benzoic acid, has a role as an antibacterial, antimicrobial, antiparasitic, and antitrichomonal agent.
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Chloranthalactone C
0 ImagesCat. No.: HY-N16123CAS No.: 73215-91-5Chloranthalactone C (Compound 43), a lindenane-type sesquiterpenoid, is an antimalarial agent. Chloranthalactone C can be isolated from plant Chloranthus japonicas Sieb. Chloranthalactone C inhibits Chloroquine (HY-17589A)-resistant Plasmodium falciparum strain Dd2 growth. Chloranthalactone C can be used for parasitic infections research.
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Antimalarial agent 15
0 ImagesCat. No.: HY-150065CAS No.: 956928-33-9
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OAT-2068
0 ImagesCat. No.: HY-125279CAS No.: 2221950-65-6OAT-2068 is a selective, high activity and orally active inhibitor of mouse chitotriosidase (mCHIT1) (IC50=29 nM) and displays 143-fold selectivity over m AMCase (IC50=4170 nM). OAT-2068 displays a good pharmacokinetic profile and is an ideal tool to study the role of CHIT1 in biological systems, including animal models of human diseases.
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Arteflene
0 ImagesCat. No.: HY-106848CAS No.: 123407-36-3Synonyms: Ro 42-1611Arteflene is a synthetic structural analogue of artemisinin. Arteflene has antimalarial activity.
